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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE1
All Species:
14.85
Human Site:
S588
Identified Species:
36.3
UniProt:
Q8IWY4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWY4
NP_766638.2
988
107910
S588
A
I
K
T
L
R
K
S
I
G
R
Q
Q
F
Y
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
A592
A
I
R
T
L
R
K
A
V
H
R
E
Q
F
H
Rhesus Macaque
Macaca mulatta
XP_001108689
995
108761
A592
L
K
R
W
D
L
S
A
D
K
C
G
V
G
L
Dog
Lupus familis
XP_538874
1009
111038
S606
S
L
K
M
L
R
K
S
I
N
Q
D
R
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL8
1018
111587
S618
A
I
K
I
L
R
K
S
I
G
R
N
Q
F
Y
Rat
Rattus norvegicus
O88281
1574
165428
G898
G
L
C
L
C
E
A
G
Y
E
G
P
R
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
T527
T
I
R
L
L
R
K
T
I
H
R
E
Q
L
F
Chicken
Gallus gallus
O73775
704
78120
T353
Y
H
L
N
E
D
G
T
R
C
V
D
V
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
S609
T
I
R
T
L
R
K
S
I
N
R
E
Q
F
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
M525
S
C
P
L
G
H
V
M
I
D
A
G
R
C
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
89.5
64.8
N.A.
89.2
22.4
N.A.
55.9
21.2
N.A.
64.6
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
76.6
91.6
76.9
N.A.
92.6
31.8
N.A.
67.9
32.7
N.A.
77.2
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
60
0
46.6
N.A.
86.6
0
N.A.
46.6
0
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
13.3
73.3
N.A.
86.6
13.3
N.A.
73.3
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
10
20
0
0
10
0
0
0
0
% A
% Cys:
0
10
10
0
10
0
0
0
0
10
10
0
0
20
0
% C
% Asp:
0
0
0
0
10
10
0
0
10
10
0
20
0
10
0
% D
% Glu:
0
0
0
0
10
10
0
0
0
10
0
30
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
10
% F
% Gly:
10
0
0
0
10
0
10
10
0
20
10
20
0
10
0
% G
% His:
0
10
0
0
0
10
0
0
0
20
0
0
0
0
20
% H
% Ile:
0
50
0
10
0
0
0
0
60
0
0
0
0
0
0
% I
% Lys:
0
10
30
0
0
0
60
0
0
10
0
0
0
0
0
% K
% Leu:
10
20
10
30
60
10
0
0
0
0
0
0
0
10
20
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
20
0
10
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
50
0
0
% Q
% Arg:
0
0
40
0
0
60
0
0
10
0
50
0
30
0
0
% R
% Ser:
20
0
0
0
0
0
10
40
0
0
0
0
0
0
0
% S
% Thr:
20
0
0
30
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
10
0
20
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _